Artvigil 150mg

Artvigil 150 mg is a cognitive activator for wakefulness it is used in treating Narcolepsy, Obstructive sleep Apnea and Work-shift Disorder. It works by increasing focus and alertness by modulating neurotransmitters like dopamine, norepinephrine, histamine and orexin. It contains armodafinil as an active ingredient with R-isomer which is responsible for wakefulness effect.

How does Artvigil 150 mg work?

• Wakefulness-promoting agent i.e., Armodafinil containing Artvigil 150 mg it may work by decreasing dopamine reuptake and raising extracellular dopamine concentrations, particularly in the prefrontal cortex, nucleus accumbens, and striatum. Executive function, motivation, and sustained attention may get enhanced.
• Armodafinil inhibits the norepinephrine and there is increase in synaptic norepinephrine in arousal-promoting centers like the locus coeruleus, resulting in enhanced vigilance and reaction time.
• Hypothalamic histamine get release from the tuberomammillary nucleus-a major wake-promoting neurotransmitter that inhibits sleep-inducing areas, such as the ventrolateral preoptic nucleus.

Key Features

Usage

Artvigil 150 can be used in the condition like:

• Narcolepsy
• Obstructive sleep Apnea
• Shift-work Disorder i.e., night shift workers, Students etc those who required wakefulness and focus.

Dosage

• Starting dose of Artvigil is 150 mg can be taken once a day.
• Do not exceed the dose by your own prior consult your healthcare provider to avoid any unwanted interactions.
• Dosage may vary from person to person depending upon their tolerance and requirement.

Side effects

• Headache
• Nausea
• Dry Mouth
• Dizziness
• Insomnia
• Anxiety or nervousness
• Suicidal thoughts

Interactions

• Artvigil efficacy gets decrease after interacting with drugs like Carbamazepine, Phenytoin, Phenobarbital, Rifampin that induce CYP3A4 increase metabolism of armodafinil that reduce plasma concentrations may decrease its efficacy.
• CYP2C19 may increase levels of drugs like Diazepam, Phenytoin, Omeprazole, and Clopidogrel as armodafinil is weak inhibitor of CYP2C19.
• Armodafinil may induce CYP2C9 slightly could decrease warfarin metabolism this can lead to side effects.
• It may interact with alcohol, so it is avoided while taking such medications.

Pharmacokinetics

• Absorption: Rapid absorption is seen when given orally, with peak plasma concentrations in 2 to 4 hours.
• Metabolism: Highly metabolized by the liver; major pathway by CYP3A4.
• Elimination: Half-life: 12-15 hours.
• Excretion: Metabolites: main route 60% in urine and 30% in

Precautions

• During pregnancy and breastfeeding armodafinil may reacts adversely and may affects fetus so it should be avoided.
• Consult a healthcare provider or doctor prior using any of medications if you are with any prior medical history like cardiac or kidney related issues.
• Use with caution if you are with any psychotic history or mental illness or anxiety
• Avoid alcohol or any addictive items as this may increase the risk of side effects.

Conclusion

Artvigil 150 mg is a cognitive activator for wakefulness it is used in treating Narcolepsy, Obstructive sleep Apnea and Work-shift Disorder. It works by increasing focus and alertness by modulating neurotransmitters like dopamine, norepinephrine, histamine and orexin. It contains armodafinil as an active ingredient with R-isomer which is responsible for wakefulness effect. It may show some side effects like nausea, dizziness, headache, insomnia and anxiety. This side effects may vary from individual to individual so need to consult your healthcare provider prior taking any such medications.

FAQs

1. What for Artvigil 150 mg is used?
Artvigil 150 mg is a cognitive activator for wakefulness it is used in treating Narcolepsy, Obstructive sleep Apnea and Work-shift Disorder.

2. How does Artvigil 150 mg works?
Artvigil 150 mg may works by increasing focus and alertness by modulating neurotransmitters like dopamine, norepinephrine, histamine and orexin.

3. How fast Artvigil works?
Artvigil may reaches peak concentration at just 2-4 hours.

4. What can be the ideal dose of Artvigil 150 mg?
Dosage may depend upon individual, starting dose can be Artvigil 150 mg, it can be taken once a day.

5. Who should avoid taking Artvigil 150 mg?
Pregnant and breast-feeding women and the one with prior medical conditions like psychotic history, cardiac or kidney issues should avoid taking any such medications.