Modafresh 200 mg is a medication used to treat excessive sleep disorders like Narcolepsy, Shift Worker Sleep Disorder and Sleep Apnea. The medication is usually taken in the morning for Sleep Apnea and Narcolepsy. For Shift Worker Sleep Disorder, the medication should be taken an hour prior to the shift.
MECHANISM OF ACTION
The mechanism of action of Modafresh 200 mg is still unknown but the basic mechanism includes:
Modafinil inhibits the dopamine transporter (DAT), blocking dopamine reuptake and increasing extracellular dopamine levels in the brain, particularly in regions like the nucleus accumbens and striatum. It increases histamine release in the hypothalamus, contributing to wakefulness – histamine is a key arousal neurotransmitter. It activates orexin/hypocretin neurons in the hypothalamus, another system critical for maintaining wakefulness.
KEY FEATURES
| About Modafresh 200 mg | |
| Drug class: Wakefulness promoting agent | |
| Chemical class: Diphenylmethanes |
| Product details | |
| Composition | Active ingredient:
Inactive ingredients:
|
| Dosage Form | Tablet |
| Route of administration | Oral |
| Packaging | Blister Pack |
| Pack size | 10*10 |
| Strength | 200 mg |
| Used for | Excessive sleep disorder |
| Approximate Onset of action | 30 to 60 minutes |
| Duration of action | 10 to 12 hours |
| Shelf life | 24 months after the manufacturing date |
| Manufacturer | Sunrise Pharma |
| Storage Instructions | Store at room temperature away from sunlight and moisture |
USES
- Obstructive Sleep apnea
- Narcolepsy
- Shift Worker Sleep Disorder
- Improve wakefulness and alertness during daytime
- Support mental performance and productivity by reducing fatigue
DOSAGE
The standard adult dosage of Modafresh 200 mg is one dose taken once daily. The medication can be taken with or without food. This medication should only be used under a physician’s guidance, particularly for individuals with pre-existing liver or kidney conditions.
SIDE EFFECTS
- Heartburn
- Nausea
- Vomiting
- Headache
- Nosebleed
- Excessive thirst
- Flushing
- Sweating
- Confusion
- Uncontrollable shaking of the body parts
- Back pain
- Depression (serious and rare)
- Hallucinations (serious and rare)
INTERACTIONS
Modafinil may interact with the following medications:
- Some anticonvulsant medications
- Anticoagulants
- Hormonal contraceptives
- Certain antidepressants
- Opioids
- Drugs metabolized through specific liver enzyme pathways
It may also interact with the following substances:
- Caffeine such as coffee, sodas, etc.
- Alcohol
- Grapefruit or grapefruit juice
PRECAUTIONS & WARNINGS
- Keep the medication away from children and pets.
- Skip the missed dose and do not exceed the prescribed limit.
- Do not double the dose to make up for the missed one.
- Inform your physician about the prescribed and non-prescribed medications that you use.
- Avoid the medication if you are allergic to modafinil, armodafinil or any other ingredients.
- Avoid drinking alcohol while taking Modafresh 200 mg.
- Modafinil may be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your physician.
CONCLUSION
Modafresh 200 mg is used as a part of treatment of sleep disorders like Narcolepsy, Shift Worker Sleep Disorder and Obstructive Sleep Apnea. Although it can be a helpful component of treatment if taken appropriately, it is not a cure for sleep disorders. Like any medication, you should take the recommended dosage, use it responsibly, and see a physician.
David Thompson –
Modafresh 200 mg helped me stay awake while I worked long hours. When I took it as directed, it helped me focus better.