Vigilit 150 mg is a wakefulness-promoting medication containing Armodafinil, the pharmacologically active enantiomer of modafinil. It is used to manage excessive daytime sleepiness associated with three clinically recognized conditions: narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder.
MECHANISM OF ACTION
Armodafinil is primarily a weak dopamine reuptake inhibitor though its competitive binding to the cell membrane dopamine transporter (DAT). This interaction with DAT and the subsequent increase in a dopaminergic tone is central to its wake-promoting effects. It also has additional effects on other CNS systems such as glutamate, GABA (gamma aminobutyric acid), histamine and orexin pathways.
KEY FEATURES
| About Vigilit 150 mg | |
| Drug class: Wakefulness promoting agent | |
| Chemical class: Diphenylmethanes |
| Product details | |
| Composition | Active ingredient:
Inactive ingredients:
|
| Dosage Form | Tablet |
| Route of administration | Oral |
| Packaging | Blister Pack |
| Pack size | 10*10 |
| Strength | 150 mg |
| Used for | Excessive sleep disorder |
| Approximate Onset of action | 30 to 60 minutes |
| Duration of action | 10 to 12 hours |
| Shelf life | 24 months after the manufacturing date |
| Storage Instructions | Store at room temperature away from sunlight and moisture |
USES
Vigilit 150 mg is used for:
- Extreme sleepiness due to sleep disorders like Narcolepsy, Shift Worker Sleep Disorder and Obstructive Sleep Apnea.
- Treatment-resistant depression
- Cognitive function improvement
- Bipolar depression
DOSAGE
Narcolepsy: 150 mg or 150 mg given once in the morning
Obstructive Sleep apnea-hypopnea syndrome (OSAHS): The recommended dose is 150 mg or 150 mg given once in the morning.
Moderate to severe Chronic Shift Worker Sleep Disorder: 150 mg daily approximately one hour before the shift begins.
SIDE EFFECTS
The most common adverse effects reported in trials are:
- Headache
- Nausea
- Insomnia
- Dizziness
- Anxiety
- Back pain
- Diarrhea
- Rhinitis
- Dyspepsia
INTERACTIONS
Vigilit 150 mg reacts with the following medications:
- Antidepressants
- Anticoagulants like Warfarin Opioids
- Hormonal contraceptives
- SSRIs (Selective Serotonin Reuptake Inhibitors)
- MAO (Monoamine oxidase) inhibitors
- Antifungal medications like Ketoconazole, Itraconazole, etc.
- Immunosuppressants
It can also interact with the following diseases:
- Hypertension
- Cardiovascular issues
- Psychiatric disorders
- Hepatic dysfunction
PRECAUTIONS & WARNINGS
- Armodafinil does not completely cure sleepiness. Avoid driving or using dangerous machineries until you know how the medication affects you.
- Use with caution if you have a history of mania, psychosis, severe depression.
- It is highly advised to avoid alcohol consumption.
- Do not self-administer.
- Use a second non-hormonal method (like condoms) while taking armodafinil and for one month after your last dose.
- Watch for swelling of your face, eyes, lips, tongue, or throat, and trouble swallowing or breathing.
CONCLUSION
Vigilit 150 mg, a medication that consists of armodafinil works by inhibiting the dopamine reuptake. The medication might interact with other medications and may lead to adverse effects. It should be used under medical supervision with attention to individual medical history, particularly cardiovascular and psychiatric conditions.
Delisha –
Vigilit 150 mg is the best to control my excessive sleepiness make me feel fresh.